@article{100219, keywords = {Leprosy, Atypical, mimicker}, author = {Kumari S and Verma GK and Negi AK and Sharma A}, title = {Lepra Reactions: Mimickers and Mirror to Unmask Complex Cases of Leprosy}, abstract = {

Leprosy is a silent disease with protean manifestations, especially during lepra reactions (LRs). Cases with atypical leprosy or LR simulate a number of conditions misdiagnosed frequently. Here, three classical cases of leprosy are reported for their complex presentation. Leprosy was hidden in Case 1 due to co-existing diabetes. COVID vaccination induced LR unmasked all leprosy lesions, which were extensive, large, bizarre and spreading to various immune zones. Case 2 presented with high-grade fever, tachycardia, generalized erythema and body aches. A detailed workup unveiled his leprosy with a rare presentation of Type 1 lepra reaction (T1LR) with erythroderma and severe systemic symptoms. Case 3 mimicked sarcoidosis and lupus erythematosus (LE) on routine workup. She had facial lesions in the malar area, photosensitivity, joint pains, raised angiotensin-converting enzyme (ACE) levels and positive anti-nuclear antibodies. Peri-appendageal granulomas on histopathology and therapeutic response to multidrug therapy helped in the early diagnosis of leprosy.

}, year = {2023}, journal = {Indian Dermatology Online Journal}, volume = {15}, pages = {500-503}, publisher = {Medknow}, issn = {2229-5178, 2249-5673}, url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152462/pdf/IDOJ-15-500.pdf}, doi = {10.4103/idoj.idoj_294_23}, language = {ENG}, }