@article{100950,
  keywords = {Type 1 reactions, Leprosy, Neuritis, Steroid Therapy, Human immunodeficiency virus (HIV)},
  author = {Bwire R and Kawuma H},
  title = {Type 1 reactions in leprosy, neuritis and steroid therapy: the impact of the human immunodeficiency virus},
  abstract = {<p>The incidence of type 1 reactions and neuritis among HIV seronegative and HIV seropositive leprosy patients was investigated. HIV seropositivity was associated with an increased incidence of type 1 reactions among multibacillary (MB) patients, which were observed in 9 of 12 seropositive MB patients and in 8 of 40 HIV seronegative MB patients (<em>P</em>&nbsp;&lt; 0 · 0005). Similarly, the incidence of neuritis was significantly increased among the HIV seropositive MB patients, of whom 8 developed acute neuritis compared to 3 of the HIV seronegative patients (<em>P</em>&nbsp;&lt; 0 · 0005). There was no significant difference between the numbers of paucibacillary HIV seropositive and HIV seronegative patients who developed these complications. Both the HIV seronegative and HIV seropositive patients showed a similar response to steroid therapy for the management of acute neuritis.</p>
},
  year = {1994},
  journal = {Transactions of the Royal Society of Tropical Medicine and Hygiene},
  volume = {88},
  pages = {315-316},
  publisher = {Oxford University Press (OUP)},
  issn = {0035-9203},
  doi = {10.1016/0035-9203(94)90098-1},
  language = {ENG},
}