@article{101386, keywords = {Hansen disease, leprosy, Nonhealing ulcer, PRF, Platelet rich fibrin, Treatment, Trophic ulcer}, author = {Vendhan S and Neema S and Vasudevan B and Krishnan L and Gera V}, title = {Platelet-rich fibrin therapy in the management of nonhealing trophic ulcers due to underlying leprous neuropathy.}, abstract = {

Autologous platelet-rich fibrin (PRF) therapy is beneficial in the treatment of nonhealing ulcers. We present a case series of nonhealing, trophic ulcers with underlying leprous neuropathy, treated successfully with PRF therapy. It was a prospective study, conducted in a tertiary care hospital in the western Maharashtra, India between April 2021 and March 2022. A total of 11 patients with 18 nonhealing trophic ulcers were included in the study and consisted of 8 men and 3 women. The patient's median age was 41 years (range, 33-68), the median size of the ulcers was 4 cm (range: 1-12 cm), the median duration of ulcers was 20 weeks (16-30 weeks), and time to heal after starting treatment was 4 weeks (range: 1-8 weeks). PRF is an easy-to-use, simple, safe, effective, and economical treatment for the management of trophic ulcers.

}, year = {2024}, journal = {Journal of cutaneous and aesthetic surgery}, volume = {17}, pages = {262-265}, month = {01/2024}, issn = {0974-2077}, url = {https://pmc.ncbi.nlm.nih.gov/articles/PMC11497549/pdf/JCAS-17-262.pdf}, doi = {10.4103/JCAS.JCAS_192_22}, language = {ENG}, }