@article{101450,
  keywords = {Covid-19, Mycobacterium w, Cancer, immune therapy, leprosy, Tuberculosis, Vaccine},
  author = {Stefan K and Gordon R and Rolig A and Honkala A and Tailor D and Davis L and Modi R and Joshipura M and Khamar B and Malhotra S},
  title = { Mycobacterium w - a promising immunotherapeutic intervention for diseases},
  abstract = {<p>Immunomodulating agents interact with the immune system and alter the outcome of specific immune processes. As our understanding of the immune system continues to evolve, there is a growing effort to identify agents with immunomodulating applications to use therapeutically to treat various diseases. (Mw), a heat-killed mycobacterium, is an atypical mycobacterial species that possesses strong immunomodulatory properties. Mw was initially evaluated as an immune-therapeutic against leprosy, but since then Mw has generated a lot of interest and been studied for therapeutic applications across a host of diseases, such as pulmonary tuberculosis, tuberculous pericarditis, sepsis, lung cancer, and more. This article summarizes a large body of work published in the past five decades, describing various aspects of Mw and its potential for further therapeutic development.</p>
},
  year = {2024},
  journal = {Frontiers in immunology},
  volume = {15},
  pages = {1-20},
  month = {01/2024},
  issn = {1664-3224},
  url = {https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1450118/pdf},
  doi = {10.3389/fimmu.2024.1450118},
  language = {ENG},
}