@article{10887, keywords = {Animals, Anti-Bacterial Agents, Cefoxitin, Cefuroxime, Cephalosporins, Female, leprosy, Mezlocillin, Mice, Mycobacterium leprae, Penicillins}, author = {Shepard C C and Van Landingham R M and Walker L L and Good R C}, title = {Activity of selected beta-lactam antibiotics against Mycobacterium leprae.}, abstract = {

Twelve beta-lactam antibiotics were tested for activity against Mycobacterium leprae growing in the foot pads of mice. Two cephalosporins (7-aminocephalosporanic acid and cefuroxime) and one cephamycin (cefoxitin) showed significant activity against M. leprae, and one penicillin (mezlocillin) exerted possible growth-promoting activity. These results suggest that particular molecular structures may be required for activity against M. leprae.

}, year = {1987}, journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association}, volume = {55}, pages = {322-7}, month = {1987 Jun}, issn = {0148-916X}, language = {eng}, }