@article{12111,
  keywords = {Antibodies, Viral, Antibody Specificity, Gels, Humans, Immunodiffusion, Infectious Mononucleosis, leprosy, Lupus Erythematosus, Systemic, Multiple Sclerosis, Neoplasms, Newcastle disease virus, Sepharose, Syphilis},
  author = {Powell J A and Kano K and Milgrom F},
  title = {Specificity of antibodies to Newcastle disease virus.},
  abstract = {<p>Specificity of antibodies to Victoria strain of Newcastle disease virus (NDV) found in infectious mononucleosis (IM) and other pathologic sera was investigated by agglutination of NDV-modified human O red blood cells, as well as by immunodiffusion and enzyme immunoassay with various preparations of the virus. These studies clearly demonstrated that the NDV antibodies are distinct from P-B or H-D antibodies. The unexpected observation that guinea pig kidney (GPK) tissues absorbed NDV antibodies allowed their classification into a group of 'GPK-positive' heterophile antibodies. The simultaneous occurrence of the NDV antibodies and H-D antibodies in IM and other diseases suggests the possibility that multiple new antigenic determinants, especially those of carbohydrate nature, may appear due to the alteration of self-antigens as a result of various pathologic processes.</p>},
  year = {1985},
  journal = {International archives of allergy and applied immunology},
  volume = {76},
  pages = {336-40},
  month = {1985},
  issn = {0020-5915},
  doi = {10.1159/000233717},
  language = {eng},
}