@article{12200, keywords = {Animals, Cercopithecidae, leprosy, Male, Respiratory System, Skin, Urogenital System}, author = {Baskin G B and Wolf R H and Gormus B J and Martin L N and Walsh G P and Binford C H and Meyers W M and Malaty R}, title = {Experimental leprosy in the mangabey (Cercocebus atys): necropsy findings.}, abstract = {

A mangabey monkey (Cercocebus atys) was inoculated intravenously and intracutaneously with acid-fast bacilli (AFB) from a mangabey with spontaneously acquired leprosy. It developed generalized lepromatous leprosy and died 46 months after inoculation. Necropsy revealed severe lepromatous infiltrates in the skin, nasal mucosa, peripheral nerves, and testicles. Internal organs were only minimally involved. The lesions seen at necropsy were very similar to those seen in untreated cases of human lepromatous leprosy. These findings further substantiate the mangabey monkey as a suitable animal model for the study of lepromatous leprosy.

}, year = {1985}, journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association}, volume = {53}, pages = {269-77}, month = {1985 Jun}, issn = {0148-916X}, language = {eng}, }