@article{17358, keywords = {Adult, Animals, Antimony Sodium Gluconate, Antiprotozoal Agents, Diagnosis, Differential, Female, Humans, Leishmania donovani, Leishmaniasis, Cutaneous, Leishmaniasis, Visceral, leprosy, Male}, author = {Dhar S and Kaur I and Dawn G and Sehgal S and Kumar B}, title = {Post-kala-azar dermal leishmaniasis mimicking leprosy: experience with 4 patients, with some unusual features in 1.}, abstract = {

We report on 4 cases of post-kala-azar dermal leishmaniasis (PKDL). History of kala-azar was available in all 4 patients. Slit-skin smears (SSS) for leishmania donovani (LD) bodies were negative in all 4. In 3 patients hypopigmented lesions were present over the face. Papules and nodules over his lips, tongue, scrotum and dactylitis were some unusual features observed in 1 patient. Histopathological examination showed LD bodies in 2 patients; histopathology was nonspecific in the other 2. All the patients were treated with sodium stibogluconate, 20 mg/kg/day. Infiltrated papules and nodules had subsided by 3 months, while hypopigmented macules took longer to improve. In 3 patients there had previously been a misdiagnosis as leprosy sufferers and they had been treated with antileprosy drugs. Clinical and histopathological differences between PKDL and leprosy are discussed.

}, year = {1995}, journal = {Leprosy review}, volume = {66}, pages = {250-6}, month = {1995 Sep}, issn = {0305-7518}, url = {http://leprev.ilsl.br/pdfs/1995/v66n3/pdf/v66n3a10.pdf}, doi = {10.5935/0305-7518.19950029}, language = {eng}, }