@article{17402, keywords = {Adult, Africa, Age Factors, Enzyme-Linked Immunosorbent Assay, Hepacivirus, Hepatitis Antibodies, Hepatitis C, Hepatitis C Antibodies, Humans, Immunoenzyme Techniques, leprosy, Middle Aged, Prevalence, Yemen}, author = {Denis F and Aussel L and Ranger S and Martin P and Itoua-N'Gaporo A and Frommel D and Teckle-Haimanot R T and Sangare A and M'Boup S and Millan J}, title = {Prevalence of antibodies to hepatitis C virus among patients with leprosy in several African countries and the Yemen.}, abstract = {

The prevalence of anti-HCV was determined in 1,309 leprosy patients and a control group of 1,469 subjects from 6 sub-Saharan African countries and the Yemen. Sera found positive by an initial second generation ELISA were subjected to 3 additional confirmatory tests. The anti-HCV prevalence in leprosy patients (7.1%) was significantly higher than in the control group (2.6%). HCV seroprevalence increased with age in both the control and leprosy groups. No statistically significant difference could be found between anti-HCV prevalence and the several clinical forms of leprosy among patients. The results of this study indicate a high degree of exposure or chronic carriage of hepatitis C among leprosy patients.

}, year = {1994}, journal = {Journal of medical virology}, volume = {43}, pages = {1-4}, month = {1994 May}, issn = {0146-6615}, doi = {10.1002/jmv.1890430102}, language = {eng}, }