@article{21493, keywords = {Antimetabolites, Antineoplastic, Cell Transformation, Neoplastic, Deoxycytidine, Diagnostic Errors, Disease Progression, Granuloma, Humans, leprosy, Magnetic Resonance Imaging, Male, Middle Aged, Muscle Weakness, Mycosis Fungoides, Skin Neoplasms, Treatment Outcome}, author = {Siriphukpong S and Pattanaprichakul P and Sitthinamsuwan P and Karoopongse E}, title = {Granulomatous mycosis fungoides with large cell transformation misdiagnosed as leprosy.}, abstract = {

BACKGROUND: Granulomatous mycosis fungoides is an unusual histopathological variant of cutaneous T-cell lymphoma without clinical distinction from classic mycosis fungoides. Symptoms associated with peripheral nerve involvement have rarely been reported in the literature.

CASE REPORT: The authors described a case of granulomatous MF stage IIB with large cell transformation who initially presented with leprosy-like condition and chronic left peroneal neuropathy The patient received six courses ofgemcitabine with greater than 90% improvement of skin lesions. The rest of the lesions were successfully treated with local electron beam radiation.

CONCLUSION: Granulomatous MF with neuropathy can be clinically misdiagnosed if there is no histopathological and immunohistochemical finding to support the diagnosis of lymphoma.

}, year = {2010}, journal = {Journal of the Medical Association of Thailand = Chotmaihet thangphaet}, volume = {93}, pages = {1321-6}, month = {2010 Nov}, issn = {0125-2208}, url = {http://www.mat.or.th/journal/files/Vol93_No.11_1321_6270.pdf}, language = {eng}, }