@article{21683,
  keywords = {Anti-Bacterial Agents, Bacteriological Techniques, DNA gyrase, DNA Topoisomerase IV, Drug Resistance, Bacterial, Microbial Sensitivity Tests, Mutation, Mycobacterium leprae, Mycobacterium tuberculosis, Quinolones, Topoisomerase II Inhibitors},
  author = {Kim H and Suzuki H and Matsuoka M and Matsuba T and Yokoyama K and Nakajima C and Suzuki Y},
  title = {[Molecular mechanism of the acquisition of new-quinolone resistance in Mycobacterium leprae and M. tuberculosis and rapid differentiation methods for resistant bacilli].},
  abstract = {<p>Drugs included in new-quinolone are used for the treatment of leprosy with single lesion. These drugs are also known to be effective drugs for the treatment of multi-drug resistant M. tuberculosis. Recent emergence of new-quinolone resistant M. leprae and M. tuberculosis enforced the urgent elucidation of the mode of emergence of new-quinolone resistant strains. In this review, new-quinolone drugs, their mode of action and mechanism of acquisition of resistance by M. leprae and M. tuberculosis were explained. And rapid differentiation methods for resistant bacilli were also introduced.</p>},
  year = {2011},
  journal = {Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association},
  volume = {80},
  pages = {17-27},
  month = {2011 Feb},
  issn = {1342-3681},
  language = {jpn},
}