@article{25487, author = {Savage J and Levis W}, title = {The utility of QuantiFERON-TB Gold assay in patients with leprosy: A possible measure of anergy}, abstract = {
We recently reported a tuberculosis-negative patient with leprosy, who displayed a giant purified protein derivative (PPD) reaction and had a positive QuantiFERON-TB Gold (QTF; Cellestis, Valencia, CA) test result.1 Concurrently, work was published showing Mycobacterium tuberculosis antigens, early secretory antigenic target (ESAT)-6 kd and culture filtrate protein (CFP)-10 kd, are cross-reactive with M leprae and can lead to false-positive QTF results.2 This supports the notion that QTF assays cannot reliably measure, in patients with leprosy, latent infection with M tuberculosis.
}, year = {2014}, journal = {Journal of the American Academy of Dermatology}, volume = {71}, pages = {996 - 997}, issn = {01909622}, doi = {10.1016/j.jaad.2014.05.028}, language = {eng}, }