@article{26424, keywords = {HIV, Epidemiology, Co-infections}, author = {Papotto PH and Maeda SM and Tomimori J and Xavier MB and Rizzo LV and Kallas EG and Carvalho KI}, title = {New Players in the Same Old Game: Disturbance of Group 2 Innate Lymphoid Cells in HIV-1 and Mycobacterium leprae Co-infected Patients.}, abstract = {

Leprosy control is achieved through a fine-tuning of TH1 and TH2 immune response pattern balance. Given the increasing epidemiological overlay of HIV and M. leprae infections, immune response in co-infected patients consists in an important contemporary issue. Here we describe for the first time the innate lymphoid cells compartment in peripheral blood of leprosy and HIV/M. leprae co-infected patients, and show that co-infection increases group 2 innate lymphoid whilst decreasing group 1 innate lymphoid cells frequencies and function.

}, year = {2015}, journal = {PLoS neglected tropical diseases}, volume = {9}, pages = {e0004030}, issn = {1935-2735}, url = {http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004030 }, doi = {10.1371/journal.pntd.0004030}, language = {eng}, }