@article{27258,
  author = {Chakrabarti S and Pal S and Biswas BK and Bose K and Pal S and Pathak S},
  title = {Clinico-Pathological Study of Cutaneous Granulomatous Lesions- a 5 yr Experience in a Tertiary Care Hospital in India.},
  abstract = {<p><strong>BACKGROUND: </strong>Granulomatous dermatoses are common skin pathology, often need histopathological confirmation for diagnosis. Histologically six sub-types of granulomas found in granulomatous skin diseases- tuberculoid, sarcoidal, necrobiotic, suppurative, foreign body &amp; histoid type. The aims of the present study were clinico-pathological evaluation of granulomatous skin lesions and their etiological classification based on histopathological examination.</p>

<p><strong>METHODS: </strong>It was a five years (Jan 2009- Dec 2013) retrospective study involving all the skin biopsies. Detailed clinical and histopathological features were analyzed and granulomatous skin lesions were categorized according to type of granuloma &amp; etiology. Special stains were used in few cases for diagnostic purpose.</p>

<p><strong>RESULTS: </strong>Among 1280 skin biopsies, 186 cases (14.53%) were granulomatous skin lesions with a ratio 1:24. In histopathological sub-typing, tuberculoid granuloma was most common type (126 cases, 67.74%). Most common etiology of granuloma in the study was leprosy (107 cases, 57.52%). Other etiologies were cutaneous tuberculosis, foreign body granulomas, fungal lesions, cutaneous leishmaniasis, sarcoidosis and granuloma annulare.</p>

<p><strong>CONCLUSION: </strong>Histopathology is established as gold standard investigation for diagnosis, categorization and clinico-pathological correlation of granulomatous skin lesions.</p>
},
  year = {2016},
  journal = {Iranian journal of pathology},
  volume = {11},
  pages = {54-60},
  issn = {1735-5303},
  url = {http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749196/pdf/ijp-11-054.pdf},
  language = {eng},
}