@article{30337,
  keywords = {Treatment, Nitazoxanide, Mycobacterium leprae, leprosy},
  author = {Bailey MA and Na H and Duthie M and Gillis T and Lahiri R and Parish T},
  title = {Nitazoxanide is active against Mycobacterium leprae.},
  abstract = {<p>Nitazoxanide (NTZ) is an anti-parasitic drug that also has activity against bacteria, including Mycobacterium tuberculosis. Our data using both radiorespirometry and live-dead staining in vitro demonstrate that NTZ similarly has bactericidal against M. leprae. Further, gavage of M. leprae-infected mice with NTZ at 25mg/kg provided anti-mycobacterial activity equivalent to rifampicin (RIF) at 10 mg/kg. This suggests that NTZ could be considered for leprosy treatment.</p>
},
  year = {2017},
  journal = {PloS one},
  volume = {12},
  pages = {e0184107},
  issn = {1932-6203},
  url = {http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184107&type=printable},
  doi = {10.1371/journal.pone.0184107},
  language = {eng},
}