@article{32091,
  keywords = {leprosy, Borderline tuberculoid leprosy, Sarcoidosis},
  author = {Liu J and Wen Y and Xing Y and Wang S},
  title = {Borderline tuberculoid leprosy mimicking sarcoidosis: A case report.},
  abstract = {<p><strong>INTRODUCTION: </strong>Leprosy is a chronic infectious granulomas disease caused by Mycobacterium leprae that can manifest as a wide variety of immunological and clinical features.</p>

<p><strong>CASE SUMMARY: </strong>Here, we describe the case of a woman with clinical characteristics of borderline tuberculoid (BT) leprosy that manifested as 3 asymmetric skin lesions involving her hip and lower limbs. This unusual presentation was initially misdiagnosed as sarcoidosis because noncaseating granulomas are a histopathological feature of both diseases. Differentiation and the diagnosis of BT leprosy was achieved using real-time polymerase chain reaction (PCR) to amplify an M leprae specific DNA sequence and to detect serum antibodies specific to M leprae antigens. Accordingly, a 6-month course of multidrug therapy led to a marked improvement in the skin lesions.</p>

<p><strong>CONCLUSION: </strong>The use of auxiliary tests including real-time PCR to amplify an M leprae-specific DNA sequence, enzyme-linked immunosorbent assay, and dipstick detection of serum antibodies specific to M leprae antigens are good methods to obtain a correct diagnosis of BT leprosy.</p>
},
  year = {2018},
  journal = {Medicine},
  volume = {97},
  pages = {e11616},
  issn = {1536-5964},
  doi = {10.1097/MD.0000000000011616},
  language = {eng},
}