@article{32146,
  keywords = {Dapsone, HLA-B*13:01, leprosy, Malaysia, Severe cutaneous adverse reaction},
  author = {Ramalingam R and Too CL and Tang MM},
  title = {Dapsone Hypersensitivity Syndrome and Dapsone-induced Liver Injury in Four Malaysian Indigenous Individuals with Leprosy},
  abstract = {<p>Dapsone is part of the multi-drug therapy used in the treatment of leprosy. It can cause life-threatening hypersensitivity syndromes resulting in significant morbidity and mortality, especially among susceptible individuals such as those who are carriers of HLA-B*13:01 allele. Avoidance of dapsone in these susceptible individuals reduces the risk of dapsone-related adverse events. Herein, we report four indigenous patients with leprosy who developed dapsone hypersensitivity syndrome.</p>
},
  year = {2018},
  journal = {Malaysian journal of dermatology},
  volume = {40},
  pages = {73-79},
  url = {http://www.dermatology.org.my/pdf/Malaysian_Journal_of_Dermatology_2018_05Jul18.pdf#page=75},
  language = {eng},
}