@article{32154, author = {Worobec SM}, title = {Current approaches and future directions in the treatment of leprosy.}, abstract = {

This review surveys current treatments and future treatment trends in leprosy from a clinical perspective. The World Health Organization provides a multidrug treatment regimen that targets the bacillus which causes leprosy. Several investigational drugs are available for the treatment of drug-resistant . Future directions in leprosy treatment will focus on: the molecular signaling mechanism uses to avoid triggering an immune response; prospective studies of the side effects experienced during multiple-drug therapy; recognition of relapse rates post-completion of designated treatments; combating multidrug resistance; vaccine development; development of new diagnostic tests; and the implications of the recent discovery of a genetically distinct leprosy-causing bacillus, .

}, year = {2012}, journal = {Research and reports in tropical medicine}, volume = {3}, pages = {79-91}, issn = {1179-7282}, url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067781/pdf/rrtm-3-079.pdf}, doi = {10.2147/RRTM.S27395}, language = {eng}, }