@article{3400, keywords = {Animals, Antibodies, Protozoan, Fluorescent Antibody Technique, Humans, Leishmania donovani, Leishmaniasis, Visceral}, author = {Choudhry A and Puri A and Guru P Y and Saxena R P and Saxena K C}, title = {An indirect fluorescent antibody (IFA) test for the serodiagnosis of Kala-Azar.}, abstract = {

The IFA test developed using Leishmania donovani promastigote and amastigote antigens showed very high antibody titre in clinically and parasitologically established cases (30) of kala-azar, the geometrical mean reciprocal titre (GMRT) being 870 +/- 5.4 and 5370 +/- 1.80 respectively with the two antigens. In contrast, the GMRT of normal subjects of endemic area was only 12.44 +/- 6.19 and 80.35 +/- 1.66 respectively with these antigens. None of the subjects from non-endemic area suffering with other parasitic diseases, such as malaria, filaria, amoebiasis, leprosy or tuberculosis (20 cases each) gave a positive response to any of the antigen. The test holds promise in the diagnosis of Kala-azar.

}, year = {1992}, journal = {The Journal of communicable diseases}, volume = {24}, pages = {32-6}, month = {1992 Mar}, issn = {0019-5138}, language = {eng}, }