@article{550, keywords = {Adult, AIDS-Related Opportunistic Infections, Animals, CD4 Lymphocyte Count, Diagnosis, Differential, Female, Herpes Zoster, HIV Infections, Humans, India, leprosy, Male, Mite Infestations, Prognosis, Skin Diseases, Syndrome, Tuberculosis, Cutaneous, Viral Load}, author = {Handa S and Narang T and Wanchu A}, title = {Dermatologic immune restoration syndrome: report of five cases from a tertiary care center in north India.}, abstract = {

BACKGROUND: Dermatologic conditions are often an early clue to human immunodeficiency virus (HIV) infection. As the disease progresses and the host immunity fails, patients may develop a number of skin conditions. At this point, they have a dominant T helper 2 immunologic response. After the initiation of antiretroviral therapy, the T helper 1 response is restored, and some skin problems, paradoxically, make their appearance then.

CONCLUSION: Herpes zoster, mucocutaneous herpes, eosinophilic folliculitis, and mycobacterial infections have been known to occur at this stage. This may be because immune restoration of a host's immunity causes recognition of silent or latent infection and results in development of the condition. We report five cases that were seen at our center during a 2-year period.

}, year = {2008}, journal = {Journal of cutaneous medicine and surgery}, volume = {12}, pages = {126-32}, month = {2008 May-Jun}, issn = {1203-4754}, doi = {10.2310/7750.2008.07017}, language = {eng}, }