@article{7868,
  keywords = {Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Disability Evaluation, Disabled Persons, Humans, Incidence, Infant, Infant, Newborn, leprosy, Middle Aged, Prevalence, Severity of Illness Index, Survival Analysis, World Health Organization},
  author = {Meima A and Van Veen N and Richardus JH},
  title = {Future prevalence of WHO grade 2 impairment in relation to incidence trends in leprosy: an exploration.},
  abstract = {<p><b>OBJECTIVES: </b>To explore the relationship between leprosy incidence trends and the future prevalence of World Health Organization (WHO) grade 2 impairment caused by leprosy.</p><p><b>METHODS: </b>Three scenarios were defined to estimate incidences and prevalences of leprosy impairment beyond 2000, assuming 6%, 12% and 18% annual declines in case detection rate respectively, and 6% impairment among new patients. Case detection data from 1985 to 2000 were used for projecting leprosy incidences up to 2020. To estimate future prevalences of WHO grade 2 impairment, the survival of existing and new impaired individuals was calculated.</p><p><b>RESULTS: </b>In the 6% scenario, 410 000 new patients will be detected in 2010 and 250 000 in 2020. The number of people living with WHO grade 2 impairment in these years will be 1.3 and 1.1 million, respectively. The 12% scenario predicts that 210 000 new patients will be detected in 2010 and 70 000 in 2020. The grade 2 prevalences will be 1.2 and 0.9 million, respectively. In the 18% scenario, the incidence will be 110 000 in 2010 and 20 000 in 2020, and the grade 2 prevalences will be 1.1 and 0.8 million, respectively.</p><p><b>CONCLUSIONS: </b>Declines in numbers of people living with grade 2 impairment lag behind trends in leprosy incidence. The prevalence of people with grade 2 decreases much slower than leprosy incidence and case detection in all three scenarios. This implies that a substantial number of people will live with impairment and will need support, training in self-care and other prevention of disability interventions in the next decades.</p>},
  year = {2008},
  journal = {Tropical medicine & international health : TM & IH},
  volume = {13},
  pages = {241-6},
  month = {2008 Feb},
  issn = {1365-3156},
  url = {http://onlinelibrary.wiley.com/doi/10.1111/j.1365-3156.2007.01996.x/pdf},
  doi = {10.1111/j.1365-3156.2007.01996.x},
  language = {eng},
}