@article{9164, keywords = {Animals, DNA, Bacterial, Female, Infectious Disease Incubation Period, leprosy, Mycobacterium leprae, Pan troglodytes, Polymorphism, Single Nucleotide, Primate Diseases, Sequence Analysis, DNA}, author = {Suzuki K and Udono T and Fujisawa M and Tanigawa K and Idani G and Ishii N}, title = {Infection during infancy and long incubation period of leprosy suggested in a case of a chimpanzee used for medical research.}, abstract = {

The length of the incubation period of leprosy following Mycobacterium leprae infection has never been conclusively determined, owing to the lack of a method to demonstrate the presence of an asymptomatic infection. We report a rare case of leprosy in a chimpanzee in which a 30-year incubation period was strongly suggested by single nucleotide polymorphism (SNP) analysis.

}, year = {2010}, journal = {Journal of clinical microbiology}, volume = {48}, pages = {3432-4}, month = {2010 Sep}, issn = {1098-660X}, url = {http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937736/pdf/0017-10.pdf}, doi = {10.1128/JCM.00017-10}, language = {eng}, }