@article{93974, keywords = {Prophylaxis, Rifampicin, Single-dose rifampicin (SDR), Leprosy Post-Exposure Prophylaxis (LPEP), Toolkit}, author = {Barth-Jaeggi T and Cavaliero A and Aerts A and Anand S and Arif M and Ay SS and Aye TM and Banstola NL and Baskota R and Blaney DD and Bonenberger M and van Brakel WH and Cross H and Das V and Budiawan T and Fernando N and Gani Z and Greter H and Ignotti E and Kamara D and Kasang C and Kömm B and Kumar A and Lay S and Mieras L and Mirza F and Mutayoba B and Njakov B and Pakasi T and Richardus JH and Saunderson P and Smith CS and Stähelik R and Suriyarachchi N and Shwe T and Tiwari A and Wijesinghe MSD and van Berkel J and Plaetse B and Virmond M and Steinmann P}, title = {Profilaxis post-exposición para lepra con dosis única de rifampicina: manual para su implementación}, abstract = {Objective: Leprosy post-exposure prophylaxis with single-dose rifampicin (SDRPEP) has proven effective and feasible, and is recommended by WHO since 2018. This SDR-PEP toolkit was developed through the experience of the leprosy post-exposure prophylaxis (LPEP) programme. It has been designed to facilitate and standardise the implementation of contact tracing and SDR-PEP administration in regions and countries that start the intervention.

Results: Four tools were developed, incorporating the current evidence for SDRPEP and the methods and learnings from the LPEP project in eight countries. (1) the SDR-PEP policy/advocacy PowerPoint slide deck which will help to inform policy makers about the evidence, practicalities and resources needed for SDR-PEP, (2) the SDR-PEP field implementation training PowerPoint slide deck to be used to train front line staff to implement contact tracing and PEP with SDR, (3) the SDR-PEP generic field guide which can be used as a basis to create a location specific field protocol for contact tracing and SDR-PEP serving as a reference for frontline field staff. Finally, (4) the SDR-PEP toolkit guide, summarising the different components of the toolkit and providing instructions on its optimal use.

Conclusion: In response to interest expressed by countries to implement contact tracing and leprosy PEP with SDR in the light of the WHO recommendation of SDRPEP, this evidence-based, concrete yet flexible toolkit has been designed to serve national leprosy programme managers and support them with the practical means to translate policy into practice. The toolkit is freely accessible on the Infolep homepages and updated as required:

https://www.leprosy-information.org/keytopic/leprosy-post-exposure-prophylaxis-lpep-programme}, year = {2020}, journal = {Fontilles, Rev. Leprol.}, volume = {4}, pages = {263-272}, language = {Spa}, }