@article{94024, keywords = {HLA, HLA-G, Immune response, leprosy}, author = {da Silva C and Sampaio L and Costa MB and Cysneiros M and Sadissou I and Castilho M and de Moraes J and Donadi E and Wastoswki I}, title = {Analysis of HLA-G protein expression in leprosy.}, abstract = {

The aim of this study was to evaluate the expression of human leukocyte antigen G (HLA-G) in leprosy. Biopsy and serum samples were collected from 18 patients presenting with leprosy and from healthy controls. Samples were analyzed using immunohistochemistry and ELISA techniques. HLA-G expression was observed in biopsy samples of all patients. The healthy control samples were consistently negative for HLA-G expression. Control plasma samples displayed significantly higher HLA-G expression than those from the patients (pā€‰<ā€‰0.01). These results are the first demonstration of the expression of HLA-G in leprosy.

}, year = {2020}, journal = {Immunogenetics}, month = {06/2020}, issn = {1432-1211}, doi = {10.1007/s00251-020-01168-4}, language = {eng}, }