@article{94620,
  keywords = {Mycobacterium leprae, leprosy, mice, real time PCR},
  author = {Karamova A and Semenova V and Verbenko D and Obraztsova O and Vanchugova K and Nikonorov A and Deryabin D and Solomka V and Kubanov A},
  title = {Experimental Modeling of Leprosy in BALB/c, BALB/c Nude, CBA, and C57BL/6ТNF Mice.},
  abstract = {<p>Leprosy was modeled in an experiment on BALB/c, BALB/cNude, CBA, and C57BL/6ТNF mice using three Mycobacterium leprae strains obtained from patients with a diagnosis of A30 according to ICD-10 from different regions of the Russian Federation. Proliferation of M. leprae of the used strains showed a temporal-quantitative dependence on the used mouse line. CBA and BALB/cNude mice were optimal for strain R and BALB/c and BALB/cNude lines were optimal for strain I. BALB/cNude mice infected with strain I had low lifespan. M. leprae strain M showed low proliferation activity in BALB/cNude and C57BL/6ТNF mice.</p>},
  year = {2020},
  journal = {Bulletin of experimental biology and medicine},
  month = {10/2020},
  issn = {1573-8221},
  doi = {10.1007/s10517-020-04991-7},
  language = {eng},
}