@article{96132, keywords = {Erythema nodosum leprosum, Lucio phenomenon, Mycobacterium leprae, leprosy}, author = {Cipriani Frade M and Coltro P and Filho FB and HorĂ¡cio G and Neto A and da Silva V and Westin A and GuimarĂ£es F and Innocentini L and Motta A and Junior J}, title = {Lucio's phenomenon: A systematic literature review of definition, clinical features, histopathogenesis and management.}, abstract = {

Leprosy is a chronic disease with clinical presentations according to the immunologic spectrum. Lepromatous form is the most advanced, with the highest transmissibility and risk of causing disabilities. Lucio's phenomenon is a rare manifestation among lepromatous patients with a rapid and severe evolution and high mortality. It is difficult to differentiate from ulcerative/necrotic erythema nodosum leprosum and has no consensus on how it should be treated. This article is a qualitative review of the literature after the introduction of multidrug therapy, aiming to bring consensus related to the clinical, laboratory and histopathological diagnostic criteria of the disease and its management.

}, year = {2021}, journal = {Indian journal of dermatology, venereology and leprology}, pages = {1-14}, month = {10/2021}, issn = {0973-3922}, url = {https://ijdvl.com/view-pdf/?article=2fb9b24a1297177fe1e8e01ff86a46fbFVLo8/4=}, doi = {10.25259/IJDVL_909_19}, language = {eng}, }