@article{96603, keywords = {Hansen disease, tratamento, QcrB inhibitors, Bacteria, leprosy, telacebec, terminal oxidase, Tuberculosis and other mycobacteria}, author = {Lahiri R and Adams L and Thomas S and Pethe K}, title = {Sensitivity of Mycobacterium leprae to Telacebec.}, abstract = {

The treatment of leprosy is long and complex, benefiting from the development of sterilizing, rapidly-acting drugs. Reductive evolution made Mycobacterium leprae exquisitely sensitive to Telacebec, a phase 2 drug candidate for tuberculosis The unprecedented potency of Telacebec against M. leprae warrants further validation in clinical trials.

}, year = {2022}, journal = {Emerging infectious diseases}, volume = {28}, pages = {749-751}, month = {03/2022}, issn = {1080-6059}, url = {https://wwwnc.cdc.gov/eid/article/28/3/pdfs/21-0394.pdf}, doi = {10.3201/eid2803.210394}, language = {eng}, }