@article{98620, keywords = {Leprosy, anti-M. Leprae, IgM antibodies}, author = {Lema T and Bobosha K and Kasang C and van Hooij A and Mengiste A and Geluk A and Aseffa and Woldeamanuel Y}, title = {Increased anti-M. Leprae PGL-I igm levels in a child who developed leprosy}, abstract = {

As part of a study that aimed at reaching those at risk of developing leprosy through screening of household contacts, a child aged 7 was included as contact of a multibacillary leprosy patient. This study was conducted in Kokosa, hot spot area in Oromia Region, Ethiopia. Compared to other contacts, this child showed increased levels of anti-M. leprae Phenolic glycolipid-I (PGL-I) IgM antibodies as assessed by up-converting lateral flow assay (UCP -LFA) at initial and second-time screening and developed leprosy three years later. Therefore, the anti-PGL-I IgM UCP-LFA can serve as an additional diagnostic field tool in leprosy control programs.

}, year = {2023}, journal = {Ethiopian Medical Journal}, volume = {60}, pages = {293-295}, issn = {2415-2420}, url = {https://www.ajol.info/index.php/emj/article/view/252306/238370}, language = {Eng}, }