@article{99361, keywords = {Atypical, leprosy, mimicker}, author = {Kumari S and Verma G. K and Negi A. K and Sharma A}, title = {Lepra Reactions: Mimickers and Mirror to Unmask Complex Cases of Leprosy}, abstract = {

Leprosy is a silent disease with protean manifestations, especially during lepra reactions (LRs). Cases with atypical leprosy or LR simulate a number of conditions misdiagnosed frequently. Here, three classical cases of leprosy are reported for their complex presentation. Leprosy was hidden in Case 1 due to co‑existing diabetes. COVID vaccination induced LR unmasked all leprosy lesions, which were extensive, large, bizarre and spreading to various immune zones. Case 2 presented with high‑grade fever, tachycardia, generalized erythema and body aches. A detailed workup unveiled his leprosy with a rare presentation of Type 1 lepra reaction (T1LR) with erythroderma and severe systemic symptoms. Case 3 mimicked sarcoidosis and lupus erythematosus (LE) on routine workup. She had facial lesions in the malar area, photosensitivity, joint pains, raised angiotensin‑converting enzyme (ACE) levels and positive anti‑nuclear antibodies. Peri‑appendageal granulomas on histopathology and therapeutic response to multidrug therapy helped in the early diagnosis of leprosy.

}, year = {2023}, journal = {Indian Dermatology Online Journal}, pages = {1-4}, url = {https://journals.lww.com/idoj/fulltext/9900/lepra_reactions__mimickers_and_mirror_to_unmask.135.aspx}, language = {Eng}, }