@article{99479,
  author = {Matono T and Suzuki S and Mori S and Ato M},
  title = {Case Report: Borderline Lepromatous Leprosy Therapy Complicated by Type 1 Leprosy Reaction and Adverse Reactions with Dapsone and Clofazimine.},
  abstract = {<p>Leprosy is a global health issue, causing long-term functional morbidity and stigma. Rapid diagnosis and appropriate treatment are important; however, early diagnosis is often challenging, especially in nonendemic areas. Here, we report a case of borderline lepromatous leprosy accompanied by dapsone-induced (neutropenia, anemia, and methemoglobinemia) and clofazimine-induced (skin discoloration and ichthyosis) side effects and type 1 leprosy reactions during administration of the multidrug therapy. The patient completely recovered without developing any deformities or visual impairment. To ensure early diagnosis and a favorable outcome, clinicians should be aware of the diminished sensation of skin lesions as a key physical finding and manage the drug toxicities and leprosy reactions appropriately in patients on multidrug therapy.</p>
},
  year = {2024},
  journal = {The American journal of tropical medicine and hygiene},
  month = {01/2024},
  issn = {1476-1645},
  url = {https://www.ajtmh.org/downloadpdf/view/journals/tpmd/aop/article-10.4269-ajtmh.22-0637/article-10.4269-ajtmh.22-0637.pdf},
  doi = {10.4269/ajtmh.22-0637},
  language = {eng},
}