@article{99608,
  keywords = {General Medicine},
  author = {Lubis RD and Yosi A},
  title = {Overview of Leprosy Reactions at Universitas Sumatera Utara Medical Faculty Hospitals between 2017 and 2021},
  abstract = {<p><strong>Background:</strong> Leprosy, or Morbus Hansen, is a chronic granulomatous disease caused by Mycobacterium leprae that involves the skin and peripheral nerves, with or without motor disorders. Leprosy reactions are immune-mediated acute or subacute inflammatory episodes that interfere with chronic disease and are classified into three types: type 1 (RR), type 2 (ENL), and the Lucio phenomenon.</p>

<p><strong>Aim: </strong>The purpose of the study is to describe the epidemiology of leprosy reactions at Universitas Sumatera Utara (USU) teaching hospitals and provide a description of factors associated with the reactions that might provide valuable information for future studies.</p>

<p><strong>Methods: </strong>This is a cross-sectional analytic study with total sampling on medical records of patients in the Dermatology and Venereology Polyclinic at H. Adam Malik Hospital Medan and USU Education Hospital in 2017–2021.</p>

<p><strong>Results:</strong> The incidence of leprosy reactions at the USU Medical Faculty Education Hospital in 2017–2021 was 41 cases. The majority of reaction types were type 2 reactions (68.3%). Risk factors for type 1 reactions were a history of reactions, being elderly, multiple lesions or nerve involvement, and co-infections, whereas the risk factors for type 2 reactions were LL, younger age, bacterial index &gt;4+, stress, and co-infections. The highest age group proportion was 18–59 years (95.1%) and was more common in men (70.7%), which mostly appeared before treatment (39.1%). The incidence of leprosy reactions was 26 new cases per 100 patients.</p>

<p><strong>Conclusion: </strong>The highest proportion of leprosy reactions was type 2, within the adult age group (18–59 years), males, and before treatment.</p>
},
  year = {2024},
  journal = {Open Access Macedonian Journal of Medical Sciences},
  volume = {12},
  pages = {116-121},
  publisher = {Scientific Foundation SPIROSKI},
  issn = {1857-9655},
  url = {https://www.researchgate.net/publication/378293524_Overview_of_Leprosy_Reactions_at_Universitas_Sumatera_Utara_Medical_Faculty_Hospitals_between_2017_and_2021/fulltext/65d1f8ab476dd15fb34420bb/Overview-of-Leprosy-Reactions-at-Universitas-Sumatera-Utara-Me},
  doi = {10.3889/oamjms.2024.11837},
  language = {Eng},
}