@article{99737, keywords = {Leprosy, electrocardiogram, QT prolongation}, author = {Yildirim E and and Secen O and Demir B and Bilen MN}, title = {Electrocardiographic Findings of Leprosy}, abstract = {

Objective: The purpose of the present study was to investigate the effect of leprosy on basic electrocardiography (ECG) parameters.

Materials and Methods: A total of 66 patients including 33 patients with leprosy (mean age: 70.06 years, 24 males) and 33 control patients (mean age: 56.66 years, 15 males) were included in the study. ECG recordings of all patients were obtained, and groups were compared in terms of heart rate, PR, QT, QTc, JTc, and T peak to T end (Tp-e) durations and branch blocks.

Results: QT (391.30 vs. 367.66, p<0.01), QTc (423.57 vs. 407.15, p<0.01), and Tp-e (74.18 vs. 66.93, p<0.001) intervals were significantly prolonged in the leprosy group. The left anterior hemiblock (LAH) was observed more in patients with leprosy (42.4% in 14 patients) than in the non-leprosy group (42.4% vs. 12.1%, p<0.01). In addition, the rate of the unifascicularblock was significantly higher in the leprosy group (39.4% vs. 9.1%, p<0.01).

Conclusion: Leprosy has a significant effect on QT, QTc, and Tp-e intervals. Prolongation of the QT, QTc, and Tp-e intervals is an indicator of leprosy's effect on the cardiac autonomic system. The ratio of the LAH is also rather high, and that may be a marker of the area where leprosy is most effective on the heart.

}, year = {2018}, journal = {Erciyes Tıp Dergisi/Erciyes Medical Journal}, volume = {40}, pages = {136-139}, publisher = {Kare Publishing}, issn = {2149-2247, 2149-2549}, url = {https://jcpres.com/storage/upload/pdfs/EMJ_40_3_136_139.pdf}, doi = {10.5152/etd.2017.0158}, language = {Eng}, }