01673nas a2200241   4500000000100000008004100001260004400042653001200086653002500098653002900123653002600152653000900178653001200187100001800199700001400217700001200231700001400243245005500257856008800312300000800400520100900408022001401417       2024                            d  bSpringer Science and Business Media LLC10aMorocco10aMycobacterium leprae10anerve conduction studies10aperipheral neuropathy10askin10aleprosy1 aBenlamkadam S1 aRaymond K1 aChraa M1 aKissani N00aNeurologic Complications of Leprosy: A Case Series  uhttps://assets.cureus.com/uploads/case_report/pdf/249080/20240508-30316-19pnxha.pdf  a1-93 a<p>Leprosy, caused by the Mycobacterium leprae complex, manifests as a chronic infection. Its hallmark presentation involves the neurocutaneous syndrome, characterized by peripheral nerve involvement and dermatologic lesions. Neurological complications significantly contribute to disability in leprosy patients. Peripheral neuropathy may manifest acutely or chronically, in either axonal or demyelinating forms, and can present as mononeuropathy, mononeuropathy multiplex, or polyneuropathy. The diverse clinical presentations emphasize the importance of considering leprosy in the differential diagnosis of peripheral neuropathy, enabling appropriate investigative approaches. Skin and nerve biopsies, slit skin smears, and nerve conduction studies serve as crucial diagnostic tools for identifying peripheral nerve involvement in leprosy. In this paper, we present three cases of leprosy with peripheral nerve involvement, discussing their clinical spectrum, diagnostic approach, and management.</p>
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