02058nas a2200229   4500000000100000008004100001260004400042653002900086653003200115653003500147653001500182653001200197653002900209100001100238700001100249700001100260700001200271245007800283490000800361520144500369022001401814       2024                            d  bSpringer Science and Business Media LLC10aGlobal Burden of Disease10ayears lived with disability10askin and subcutaneous diseases10aDermatitis10aScabies10aNon-melanoma cell cancer1 aKong Y1 aXing P1 aHuai P1 aZhang F00aThe burden of skin diseases in China: global burden of Disease Study 20190 v3163 a<p>Skin diseases continue to affect human health and cause a significant disease burden on the healthcare system.We aimed to report the changing trends in the burden of skin disease in China from 1990 to 2019, Which has an important role in developing targeted prevention strategies. We applied Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2019 analytical tools to calculate the age-standardized Prevalence and Incidence in 2019, number of years lived with disability (YLDs) and age-standardized YLDs from 1990 to 2019 of skin and subcutaneous diseases, notifiable infectious skin diseases and skin tumors in China. Among the skin and subcutaneous diseases in China in 2019, dermatitis contributed to the greatest YLD (2.17&nbsp;million, 95% uncertainty interval[UI]: 1.28–3.36). Age-standardized YLD rates for leprosy decreased from 0.09 (95%UI: 0.06–0.13) in 1990 to 0.04 (95%UI: 0.03–0.06) in 2019; the proportional decrease was 55.56% over 30 years. Age-standardized YLDs for HIV and sexually transmitted infections increased by 26% during the same time period. Age-standardized YLDs for non-melanoma skin cancer increased at a much higher rate than melanoma between 1990 and 2019. Dermatitis and scabies continue to have an important role in the burden of skin and subcutaneous disease burden in China. The burden of non-melanoma cell cancer has increased most significantly over the past three decades.</p>
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