00955nas a2200181   4500000000100000008004100001260001300042653002500055653001800080653001100098653001100109100001500120700001600135245002900151300001200180520056300192020001800755       2015                            d  bElsevier10aMycobacterium leprae10aImmune System10aT-cell10aB-cell1 aRibeiro FM1 aShoenfeld Y00aLeprosy and Autoimmunity  a583-5973 a<p>Leprosy is an infectious disease caused by&nbsp;<em>Mycobacterium leprae</em>, which affects peripheral nerves and skin. The relevance of this disease comes from complex interactions between bacilli and the host immune system that lead to different clinical findings dependent on changes in T- and B-cell responses. Severe systemic manifestations may also occur at any time during the infection and even years after treatment. This chapter describes the clinical and pathogenic features of leprosy and the interaction of leprosy with other diseases.</p>
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