01844nas a2200193   4500000000100000008004100001653003600042653001200078653001500090100002200105700002700127700001400154700001800168700001400186245018100200856008000381300000800461520118100469       2024                            d10aDegree of Disability in Leprosy10aLeprosy10aSerum IL-61 aNurisma Putri   S1 a Eka Putra Mundhofir F1 aYuniati R1 aWijayahadi  N1 aNindita Y00aCorrelation between Degree of Leprosy Disability and Serum IL-6 Levels in Patients with Leprosy Reactions: An Observational Study at the Donorojo Jepara Leprosy Hospital Center  uhttps://ejournal3.undip.ac.id/index.php/medico/article/download/45004/31488  a1-53 a<p><strong>Background</strong>: Leprosy is an infectious disease caused by Mycobacterium leprae bacteria which is still the focus of a global problem and causes disability in patients. The degree of disability in leprosy is assessed as mild and severe as a result of the inflammatory process. This study aims to determine the relationship between the degree of disability in leprosy and IL-6 serum levels as an inflammatory biomarker in leprosy patients.&nbsp;</p>

<p><strong>Methods</strong>: A Cross-sectional observational analytical study on leprosy patients aged 20-60 years, not pregnant, and undergoing treatment at Donorojo Jepara Hospital from March to April 2024. Serum IL-6 levels were analyzed using the ELISA method and tested for correlation with the degree of disability leprosy.&nbsp;</p>

<p><strong>Results</strong>: Statistical analysis of Spearman's correlation rank test shows a p value = 0.279 and the results of the line pattern on the Scatter dot graph are not linear.&nbsp;</p>

<p><strong>Conclusion</strong>: There is no correlation between serum IL-6 levels and the degree of disability in leprosy patients at Donorojo Jepara Hospital.</p>