01408nas a2200181 4500000000100000008004100001260001200042100001300054700001200067700001200079700001200091245017500103856012300278300001200401490000700413520079200420022001401212 2024 d c04/20241 aRanjan A1 aKumar A1 aSinha N1 aKumar A00aLeprosy Presenting as Distal Acquired Demyelinating Symmetric Variant of Chronic Inflammatory Demyelinating Polyneuropathy: An Atypical Manifestation of Hansan's Disease. uhttps://journals.lww.com/ijmy/fulltext/2024/13020/leprosy_presenting_as_distal_acquired.16.aspx?context=latestarticles a218-2200 v133 a

Leprosy, caused by the bacterium Mycobacterium leprae, is known to primarily affect the skin and peripheral nerves. We present a rare case of leprosy initially manifesting as demyelinating polyneuropathy. A 46-year-old female presented with progressive weakness, tingling, and numbness in her extremities. Nerve conduction studies revealed evidence of demyelination, prompting further investigations. Skin slit-skin smears confirmed the diagnosis of leprosy, with the presence of acid-fast bacilli. The patient was subsequently started on multidrug therapy, leading to significant clinical improvement. This case highlights the importance of considering leprosy as a differential diagnosis in patients presenting with demyelinating polyneuropathy, especially in endemic regions.

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