01892nas a2200241 4500000000100000008004100001260001200042653002300054653002400077653001700101653001500118653002100133100001500154700001500169700001700184700001200201245005000213856026000263300001200523490000700535520108300542022002501625 2024 d bMedknow10aHepatosplenomegaly10aLepromatous leprosy10aPancytopenia10aIchthyosis10aHemaphagocytosis1 aFernando N1 aWelhenge C1 aPremaratna R1 aUwyse A00aBorderline lepromatous leprosy: A case report uhttps://pdfs.journals.lww.com/aptm/2024/17070/borderline_lepromatous_leprosy__a_case_report.5.pdf?token=method|ExpireAbsolute;source|Journals;ttl|1722340575510;payload|mY8D3u1TCCsNvP5E421JYK6N6XICDamxByyYpaNzk7FKjTaa1Yz22MivkHZqjGP4kdS2v0J76WGAnHACH69s21C a329-3320 v173 a

Rationale: Lepromatous leprosy can have many atypical presentations, obscuring early diagnosis. We present a case of lepromatous leprosy, presenting with atypical features, which made a diagnostic dilemma.

Patient concerns: A 48-year-old man presented with bilateral lower limb oedema and scaly “ichthyosis like” skin rash in both hands and feet, hepatosplenomegaly and pancytopenia, over a course of three months, without any classical features of leprosy. A skin biopsy revealed an unexpected diagnosis of borderline lepromatous leprosy.

Diagnosis: Lepromatous leprosy.

Interventions: Multi-drug regimen treatment with rifampicin, dapsone and clofazimine for lepromatous leprosy.

Outcomes: The patient made a good clinical recovery.

Lessons: In endemic settings, clinicians should be aware of similar atypical manifestations of leprosy to face the global challenge of eradicating this chronic deforming disease.

 a1995-7645, 2352-4146