01567nas a2200289 4500000000100000008004100001260004400042653001800086653003100104653002200135653002300157653001700180653002700197653002500224653002400249653002500273100001200298700001600310700001600326700001200342700001300354245011600367856008800483300000800571520068400579022001401263 2024 d bSpringer Science and Business Media LLC10avirchow cells10a drug-induced pancytopenia10afoamy histiocytes10a fite-faraco stain10aPancytopenia10aleprosy in bone marrow10amycobacterium leprae10alepromatous leprosy10abone marrow aspirate1 aShine R1 aAmitkumar K1 aGanapathy S1 aJohn JJ1 aRoy SG J00aA Rare Cause of Pancytopenia From Lepromatous Leprosy Diagnosed in Bone Marrow Aspiration: A Bolt From the Blue uhttps://assets.cureus.com/uploads/case_report/pdf/289528/20240912-110902-eh1ugl.pdf a1-83 a
Hansen’s disease is caused by Mycobacterium leprae. The clinical presentation of lepromatous leprosy is broad, affecting patients with reduced T-cell immune response and causing anergy. Usually, the patient presents with numerous red to brown nodules over the face and auricles and is diagnosed by skin biopsy. We hereby report an unusual case of a 40-year-old man who presented with altered sensorium and fever. Lepromatous leprosy was diagnosed initially in the bone marrow aspiration without any clinical suspicion or previous skin biopsy confirmation. Bone marrow infiltration by lepra bacilli is very rare, with only a few cases reported in the literature so far.
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