01559nas a2200169   4500000000100000008004100001653001200042653002700054653002100081653002300102100001400125700001400139245006300153856008300216300001200299520107800311       2024                            d10aLeprosy10aPulmonary hypertension10aEchocardiography10aRare manifestation1 aSiregar M1 aWahidji V00aThe First Case Report of Pulmonary Hypertension in Leprosy  uhttps://journal.iha.org.ir/article_206738_9a1d9d69bc065e6afd1f823332bdd5b6.pdf  a100-1043 a<p>Leprosy is a chronic infectious disease caused by Mycobacterium leprae, an acid-fast, rodshaped bacillus. The disease predominantly affects the skin, the peripheral nerves, the mucosa of the upper respiratory tract, and the eyes. 1 The diagnosis of leprosy is based on the presence of at least 1 of 3 cardinal signs: definite loss of sensation in a pale or reddish skin patch, a thickened or enlarged peripheral nerve with loss of sensation, and/or weakness of the muscles supplied by the nerve, and the presence of acid-fast bacilli in a slit-skin smear. However, there are no reports that describe the link between leprosy and pulmonary hypertension (PH). Here, we describe a 22- year-old man who was first diagnosed with leprosy and subsequently developed PH, confirmed by echocardiography. To our knowledge, this is the first case of leprosy associated with PH with a detailed clinical description. We recommend that physicians be aware of this rare comorbidity in patients with leprosy. Early echocardiographic screening is necessary for symptomatic patients.</p>