01669nas a2200217 4500000000100000008004100001260004400042653002100086653004200107653001600149653001200165653002900177100001400206700001100220700001300231245010700244856014700351300000800498520093100506022001401437 2024 d bSpringer Science and Business Media LLC10acladophialophora10acystic subcutaneous phaeohyphomycosis10aFluconazole10aLeprosy10aone celled blastoconidia1 aKumar PBP1 aMala M1 aJacob ES00aCystic Subcutaneous Phaeohyphomycosis Caused by Cladophialophora Species in an Elderly Leprosy Patient uhttps://www.cureus.com/articles/299488-cystic-subcutaneous-phaeohyphomycosis-caused-by-cladophialophora-species-in-an-elderly-leprosy-patient# a1-93 a

Phaeoid (dematiaceous) fungi are a diverse group of species characterized by their production of the pigment dihydroxynaphthalene melanin. Although phaeoid fungi do not usually cause human infections, they are commonly found in nature as contaminants. These fungi are present in decomposing vegetation, rotting timber, and soil. However, an increase in infections is probably due to the increase in the population of individuals with compromised immune systems. An elderly female patient from the southernmost part of India, who was previously treated for leprosy, presented with multiple boggy swellings in her right hand. An appropriate sample was collected under aseptic precautions and subjected to microbiological analysis, which led to the isolation of Cladophialophora species. The patient was treated with antifungal drugs, but her condition worsened, resulting in a poor outcome.

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