01591nas a2200277   4500000000100000008004100001260001200042653001900054653001200073653002100085653000800106653002500114653001400139653001800153100001400171700001200185700001600197700001500213700001100228245011800239856007400357300001200431490000700443520084900450022001401299       2024                            d  c01/202410aHansen disease10aleprosy10aNonhealing ulcer10aPRF10aPlatelet rich fibrin10aTreatment10aTrophic ulcer1 aVendhan S1 aNeema S1 aVasudevan B1 aKrishnan L1 aGera V00aPlatelet-rich fibrin therapy in the management of nonhealing trophic ulcers due to underlying leprous neuropathy.  uhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11497549/pdf/JCAS-17-262.pdf  a262-2650 v173 a<p>Autologous platelet-rich fibrin (PRF) therapy is beneficial in the treatment of nonhealing ulcers. We present a case series of nonhealing, trophic ulcers with underlying leprous neuropathy, treated successfully with PRF therapy. It was a prospective study, conducted in a tertiary care hospital in the western Maharashtra, India between April 2021 and March 2022. A total of 11 patients with 18 nonhealing trophic ulcers were included in the study and consisted of 8 men and 3 women. The patient's median age was 41 years (range, 33-68), the median size of the ulcers was 4 cm (range: 1-12 cm), the median duration of ulcers was 20 weeks (16-30 weeks), and time to heal after starting treatment was 4 weeks (range: 1-8 weeks). PRF is an easy-to-use, simple, safe, effective, and economical treatment for the management of trophic ulcers.</p>  a0974-2077