01441nas a2200205   4500000000100000008004100001260004300042653001000085653002100095653001200116100001400128700002000142700001700162245008800179856007200267300001200339490000700351520085200358022002501210       2024                            d  bGalore Knowledge Publication Pvt. Ltd.10aCCL-210aneuropathic pain10aleprosy1 aHanjaya H1 aWidyadharma IPE1 aWidyastuti K00aCCL-2 as a Potential Biomarker for Neuropathic Pain in Leprosy: A Literature Review  uhttps://www.ijrrjournal.com/IJRR_Vol.11_Issue.11_Nov2024/IJRR64.pdf  a620-6270 v113 a<jats:p>Neuropathic pain is a debilitating symptom in leprosy patients that significantly impacts their quality of life. While the mechanisms underlying this pain remain unclear, recent research suggests a potential role for C-C motif chemokine ligand 2 (CCL-2), a chemokine involved in inflammatory processes. This literature review explores the association between CCL-2 levels and neuropathic pain in leprosy patients. We discuss the current understanding of CCL-2's role in nerve damage and inflammation, as well as its potential as a biomarker for predicting and monitoring neuropathic pain in leprosy. Understanding the role of CCL-2 in leprosy-associated neuropathic pain may lead to the development of novel therapeutic strategies and improve the management of this chronic condition.

Keywords: CCL-2, neuropathic pain, leprosy</jats:p>  a2349-9788, 2454-2237