01513nas a2200241   4500000000100000008004100001260002700042653002100069653002400090653002500114653002300139100002300162700002100185700001700206700001600223700001800239700002000257245008500277856007000362300000600432520080800438022002501246       2025                            d  bPAGEPress Publications10aLucio Phenomenon10aLepromatous Leprosy10aMycobacterium Leprae10aPulmonary Embolism1 aSajjachareonpong N1 aSudtikoonaseth P1 aKampirapap K1 aTanabodee M1 aPrunglumpoo S1 aKiatsurayanon C00aLucio phenomenon: a case report on an overlooked reaction in lepromatous leprosy  uhttps://www.pagepress.org/journals/dr/article/download/10173/9570  a93 a<p>Our patient presented with a 5-year history of chronic, asymptomatic papulonodular lesions on the extremities. The lesions spread to the face and earlobes, with new ulcerative lesions on both legs for the past 8 months. Skin biopsy was compatible with lepromatous leprosy with Lucio phenomenon. Lucio phenomenon is a rare type of leprosy reaction found mostly in neglected lepromatous leprosy cases. Unfortunately, the patient developed pulmonary embolism and passed away. This case report focuses on the clinicopathological characteristics and management of Lucio phenomenon, which is an unusual form of leprosy reaction that often carries a poorer prognosis. Importantly, physicians should be able to differentiate Lucio phenomenon from other types of leprosy reactions for prompt management.</p>
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