01502nas a2200229 4500000000100000008004100001260002600042653001200068653001600080653001200096653005400108653001700162100001600179700001700195700001800212245014300230856005300373300000600426490000700432520081900439022001401258 2025 d bSaudi Medical Journal10aLeprosy10aCase report10aMimicry10aChronic inflammatory demyelinating polyneuropathy10aSaudi Arabia1 aAlOtaibi MK1 aAlQahtani BG1 aAlQawahmed RM00aUnmasking the mimic: Leprosy neuropathy misdiagnosed as chronic inflammatory demyelinating polyneuropathy: A case report from Saudi Arabia uhttps://nsj.org.sa/content/nsj/30/2/157.full.pdf a50 v303 a
Leprosy neuropathy can mimic chronic inflammatory demyelinating polyneuropathy (CIDP), especially in non-endemic areas. We report a 72-year-old Saudi woman initially misdiagnosed with CIDP based on nerve conduction studies. The patient presented with widespread pruritus, erythematous cutaneous lesions, and progressive sensorimotor symptoms. Despite treatment with intravenous immunoglobulin, her condition worsened. Subsequent sural nerve and skin biopsies revealed acid-fast bacilli, confirming leprosy. This case highlights the importance of considering leprosy in the differential diagnosis of neuropathies, even in regions where it is rare. Nerve ultrasound, a valuable diagnostic tool in differentiating leprosy from CIDP, should be incorporated into the diagnostic workup of atypical neuropathies.
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