01468nas a2200301 4500000000100000008004100001260001700042653001800059653002100077653002300098653001100121653002500132653000900157653001600166100001200182700001300194700001600207700001500223700001500238700001200253700001500265700001400280245010000294300000800394490000700402520074300409022001401152 1986 d c1986 Jan-Dec10aAcute disease10aErythema Nodosum10aGlomerulonephritis10aHumans10aLeprosy, lepromatous10aMale10aMiddle Aged1 aNigam P1 aPant K C1 aMukhija R D1 aSharma S P1 aSaxena S P1 aKumar A1 aKapoor K K1 aGupta A K00aRapidly progressive (crescentric) glomerulonephritis in erythema nodosum leprosum: case report. a1-60 v113 a

A middle aged man (48 years) with short duration of illness (7 days) was admitted in the state of acute renal failure with erythema nodosum leprosum. He had repeated episodes of erythema nodosum leprosum in the past. His blood pressure was normal (150/80 mmHg). During his hospital stay he was in the state of progressive anaemia (Hb = 8.8 g/dl to 7.2 g/dl), oliguria (urine out-put = 250-350 ml/day), azotaemia (blood urea = 198 mg/dl to 218 mg/dl) and impaired renal function tests with fatal outcome. Kidneys were smooth, congested and weighing 150 g each with histological features of rapidly progressive (crescentric) glomerulonephritis, a result of immune complex deposition from recurrent erythema nodosum leprosum episodes.

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