01413nas a2200325 4500000000100000008004100001260001300042653001500055653001000070653000900080653002200089653002100111653001100132653001100143653001200154653000900166653001600175653002200191653001800213100001400231700001200245700001200257700001500269700001100284245004100295300001100336490000700347520071900354022001401073 1988 d c1988 Sep10aAdolescent10aAdult10aAged10aAged, 80 and over10aElectromyography10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aNeural Conduction10aPhrenic Nerve1 aDhand U K1 aKumar B1 aDhand R1 aChopra J S1 aKaur S00aPhrenic nerve conduction in leprosy. a389-930 v563 a

Phrenic nerve conduction was performed bilaterally in 22 multibacillary (BL-LL) and 18 paucibacillary (BT-TT) leprosy patients and 25 control subjects. Prolonged phrenic nerve conduction time and/or reduced amplitude of diaphragm muscle action potential beyond 2.5 standard deviations of control mean values was observed in 9 BL-LL patients (4 bilateral) and 6 BT-TT patients (all unilateral). Out of the nine BL-LL patients with phrenic nerve involvement, median motor and/or sensory nerve conduction was also abnormal in seven patients. On fluoroscopy, diaphragm movements were normal in all patients. The study documents subclinical phrenic nerve involvement in leprosy--a fact not previously recognized.

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