01340nas a2200301   4500000000100000008004100001260001300042653001200055653002000067653001200087653000900099653002300108653000900131653002200140100001500162700001300177700001500190700001500205700001400220700001600234700001500250700001300265245007900278300001100357490000700368520064900375022001401024       1985                            d  c1985 Jun10aAnimals10aCercopithecidae10aleprosy10aMale10aRespiratory System10aSkin10aUrogenital System1 aBaskin G B1 aWolf R H1 aGormus B J1 aMartin L N1 aWalsh G P1 aBinford C H1 aMeyers W M1 aMalaty R00aExperimental leprosy in the mangabey (Cercocebus atys): necropsy findings.  a269-770 v533 a<p>A mangabey monkey (Cercocebus atys) was inoculated intravenously and intracutaneously with acid-fast bacilli (AFB) from a mangabey with spontaneously acquired leprosy. It developed generalized lepromatous leprosy and died 46 months after inoculation. Necropsy revealed severe lepromatous infiltrates in the skin, nasal mucosa, peripheral nerves, and testicles. Internal organs were only minimally involved. The lesions seen at necropsy were very similar to those seen in untreated cases of human lepromatous leprosy. These findings further substantiate the mangabey monkey as a suitable animal model for the study of lepromatous leprosy.</p>  a0148-916X