02215nas a2200445   4500000000100000008004100001260000900042653001500051653001600066653001600082653001000098653002100108653001100129653002200140653001100162653001100173653002000184653001300204653001200217653002500229653000900254653001200263653002000275653003000295100001700325700001100342700002400353700001300377700001700390700001600407700001400423700001700437700001300454245010600467856008300573300000900656490000700665520108300672022001401755       1974                            d  c197410aAdolescent10aAge Factors10aBCG Vaccine10aChild10aChild, Preschool10aFemale10aFollow-Up Studies10aHumans10aInfant10aInfant, Newborn10aLepromin10aleprosy10aLongitudinal studies10aMale10aMyanmar10aTuberculin Test10aWorld Health Organization1 aBechelli L M1 aLwin K1 aGallego Garbajosa P1 aUemura K1 aSundaresan T1 aTamondong C1 aMatejka M1 aSansarricq H1 aWalter J00aBCG vaccination of children against leprosy: nine-year findings of the controlled WHO trial in Burma.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366256/pdf/bullwho00467-0097.pdf  a93-90 v513 a<p>The leprosy incidence rates so far in the vaccinated and unvaccinated children aged 5-9 and 10-14 years are similar. The BCG-vaccinated children aged 0-4 years at intake had an incidence rate lower than that of children in the control group. BCG vaccination did not protect household contacts or children aged 5-14 years not exposed in the household, and did not influence the distribution of the forms of leprosy in the cases detected. The lepromin reaction in relation to the age at intake was consistently stronger in the vaccinated children than in those of the control group; the younger the age group the more pronounced was the difference, which was only slight in the age group 10-14 years at intake. If the results of the late lepromin reaction are related to the age at onset (when the children are older than at intake), the differences between the BCG and the control groups tend to decrease. It does not seem that the BCG-vaccinated children suffer from a less serious form of leprosy than the nonvaccinated children (most of them nonreactors to tuberculin).</p>  a0042-9686