02431nas a2200373   4500000000100000008004100001260000900042653001900051653001600070653002900086653002800115653001900143653005000162653001100212653001900223653002000242653003000262653001500292653002000307653002400327653002700351653002600378653001800404653002000422100001400442700001600456700001200472700001500484245005200499300001100551490000800562520147300570022001402043       1984                            d  c198410aAdipose Tissue10aAmyloidosis10aDermatitis, Occupational10aDiagnosis, Differential10aDrug Eruptions10aHereditary Sensory and Autonomic Neuropathies10aHumans10aHypothyroidism10aInfant, Newborn10aMetabolism, Inborn Errors10aPorphyrias10aRaynaud Disease10aSclerema Neonatorum10aScleroderma, Localized10aScleroderma, Systemic10aSkin Diseases10aWerner Syndrome1 aMauduit G1 aCambazard F1 aFaure M1 aThivolet J00a[Pseudoscleroderma and sclerodermiform states].  a615-230 v1353 a<p>Pseudo-scleroderma should not be confused with true scleroderma, the prognosis of which is unpredictable and often serious. Progressive acrosclerosis must be differentiated from Raynaud's disease, congenital or hereditary disorders of unknown aetiology: Werner's syndrome, acrogeria and progeria; Rothmund-Thomson's syndrome, Steinert's disease, phenylketonuria, disorders of glycogen metabolism; metabolic disorders: mutilating acropathies, scleromyxoedema, porphyria cutanea tarda; occupational and iatrogenic disorders: acroosteolysis, toxic epidermic syndrome (Spain), scleroderma-like change induced by bleomycin, chronic graft-versus-host disease; and leprosy. Acute diffuse scleroderma should not be confused with Buschke's scleroedema, sclerema neonatorum, systemic amyloidosis and scleroderma-like changes in hypothyroidism. Linear pseudo-scleroderma is suggested by the following scleroderma-like conditions: facial hemiatrophy, acrodermatitis atrophicans, melorheostosis, pseudo-scleroderma after corticosteroid injection, and cutaneous lesions in carcinoid syndrome. Scleroderma in plaque must be differentiated from hypodermitis sclerotisans, panatrophy and localized lipoatrophies, hypodermitis after vitamin K injection, basal cell carcinoma, necrobiosis lipoidica, vitiligo, chronic radiodermatitis, cutaneous lymphatic invasion. Scleroderma-like changes after drug injection (vitamin B12, progestin), anetoderma barely resemble morphea guttata.</p>  a0003-410X